For patients & caregivers
About Coronary Artery Disease and its Treatment

Coronary Artery Disease

Coronary artery disease (CAD) affects over 15 million people in the United States. It is the leading cause of death for men and women. CAD affects the arteries that supply blood to the heart. It occurs when the passageway through the coronary arteries, or heart arteries, becomes narrowed by a buildup of plaque, including cholesterol, fatty deposits, calcium, and other substances. Known as atherosclerosis, this buildup occurs over time and reduces the flow of blood to the heart. Reduced blood flow means less oxygen is getting to the heart. This may cause mild to severe chest pains or pressure, sometimes called angina, which can spread to the arms or jaw. This can happen during stressful times, during physical activities such as work or exercise, or even at rest. If the flow of blood in a heart artery is blocked, a heart attack can occur. Anyone who experiences chest pain or signs of a heart attack should seek medical help as soon as possible.

Treatment of CAD

CAD may be managed with a combination of lifestyle changes such as exercise and diet, and medical treatment. The treatment your doctor recommends will depend on the severity of your disease. There are medicines that are given to relieve chest discomfort due to blockages, but do not treat the blockage itself. Treatments of the blockage may include:

  • Medications
  • Angioplasty with or without stent placement
  • Coronary artery bypass graft surgery (CABG)

Medical Procedures

In addition to lifestyle changes and medications, there are also medical procedures that may be performed.

  • Coronary Artery Bypass Surgery (CABG)
    CABG is also known as open heart surgery. During surgery, arteries or veins are taken from another part of the body and used to reroute blood around blocked heart arteries.
  • Angioplasty
    Also known as percutaneous transluminal coronary angioplasty (PTCA). Angioplasty is a non-surgical procedure that is performed in the hospital by threading a small tube (known as a catheter) through the groin or arm which is then passed through an artery to the site of the blockage. A small balloon located on the tip of the catheter is then slowly inflated to open the blockage. This procedure can be performed with a balloon catheter alone, or can involve the placement of a coronary stent.
  • Stent Implant
    More and more patients who have an angioplasty also have what is known as "stent placement." Stents look similar to the spring in a ball point pen. After the angioplasty procedure opens the artery, a stent is placed and expanded to fit the size of the artery. The stent remains in the artery to help keep blood flowing freely. Over time, the artery wall heals around the stent.

For more information about Coronary Artery Disease, visit the following Web sites:

  • American Heart Association
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  • Medicinenet.com
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    (Go to "Coronary Angioplasty" in the Diseases and Conditions section)
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